The Best Mastiff Mixed Breeds

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The Best Mastiff Mixed Breeds The Mastiff breed is made up of powerful dogs that are also known to be gentle giants and are also referred to as the Old English Mastiff. They are among the oldest dog breeds in the world, which is why there are many various Mastiff mixed breeds but today, we’ll be focusing on the most popular Mastiff hybrids. However, before we discuss the different mastiff mixes available today, we should first get to know the Mastiff breed. 

What is the Mastiff Dog Breed?

The Mastiff dog breed is what we call a gentle giant in the dog world, and some will tend to be lazy. They are often described as highly courageous and can serve as great watchdogs — even so, they’re rarely aggressive and will often choose to stand their ground because they know that intruders and strangers won’t stand a chance against them. A male Mastiff can grow as big as 32 inches in height and weigh between 160 to 230 pounds, while females will be smaller. 

As you can see, this is a large breed dog and will be great companions to everyone who can care for them and accommodate their impressive size. That said, we wouldn’t recommend adopting this pooch for a first-time dog owner or if you live inside a small apartment. However, if you’re a fan of large breeds and affectionate dogs, then the Mastiff may just be your next dog.        

What are the Different Mastiff Mixes? 

Below, we share some of the most well-known Mastiff mixes, some of which may surprise you. 


These canines are a mix between the Mastiff and Labrador Retriever, which results in a dog that’s as sweet as can be but will also be on its guard for your protection. Thanks to their parent breeds, they’re highly family-oriented but are also sensitive to other dogs and strangers. When living with an experienced owner, they can be great watchdogs but their large size might make them too much for children to handle so they will need supervision. 

Fortunately, Mastiff Lab mix dogs are flexible enough to train but they may still have a bit of a stubborn streak. Such big dogs will need basic training and early socialization to help them become well-adjusted adults. Make sure to give them rewards and never punish them so they don’t become aggressive or timid. 


When you cross a Mastiff with a bulldog, this is what you get — a big, brown bear that’s full of love and would do anything to please their family. However, they might be a bit too affectionate which may come off as being overprotective; some will even treat children as their own pups. If you don’t give them the proper training they need, their brawling instincts may kick in; these canines will need plenty of training to help them stay on their best behavior. 

Because of this, they will need to be slowly and carefully introduced to other pets and strangers, which will help them get a sense of ease and comfort. There will also be times when they forget how big they are and may lazily plop down beside you or on top of you since they think of themselves as lapdogs. Unfortunately, there are a few health issues associated with their size, so be sure to look out for signs of early hip dysplasia. 

Mastiff American Bulldog Mix

If you’re looking for a pet that will take guard duties to the next level, then this is the pup for you. These loving and protective dogs come with plenty of affection but have even more desire to keep their loved ones safe from danger and harm. Unlike the breed above which is half the Old English bulldog, this mixed breed is half American bulldog, so it will be vigilant with other animals and new people. 

Much like with other Mastiff mixed breeds, proper socialization and early training are a must, but you might have trouble due to their high intelligence and stubbornness. You should also know that they will be very attached to their families, so it’s best to keep them company as much as possible. When left alone for long periods, they may develop separation anxiety — their larger size may also be a problem during walks, so they will need an experienced owner.    

Mastiff Shepherd

These friendly dogs are a cross between the Mastiff and a German Shepherd, which gives you an extra-friendly pooch that you’ll call a social butterfly. They are big dogs that love to be everywhere with everyone and will tend to form a strong bond with their families. Because of their mild temperament, they can be great with young children but will still need some supervision due to their large frames.

Despite their wonderful personality traits, this designer breed will still need to be introduced properly to warm up to new faces; luckily, they’ll do well with other pets in your home. Much like every other dog, they will benefit from consistent training and early socialization to help them become better adjusted to everyday life. Lastly, you should know that these dogs are highly intelligent — while they aren’t as active as others, they will need mental stimulation to keep them entertained. 


Bull Mastweilers are what you get when you combine the Mastiff with the Rottweiler. These active dogs are known to treat kids as one of their own, and will eagerly protect them but supervision will be required due to their size. They can become overprotective due to their instincts, so early socialization is key to keeping them under control. 

Other dogs, along with strangers, will need a proper and gradual introduction, especially when they’re around family when they’re likely to become even more protective. Unfortunately, they’re not the best dogs for homes with small animals since their high prey drive may lead them on a hunt. The Mastweiler comes with a long history of hunting, so be sure to give them socialization and training at an early age to help them become loving family members. 


When you want to combine a Mastiff with a Boxer, you’ll get the Boxmas but its temperament will be highly dependent on the stronger genes. These dogs will often entertain their humans through their antics and will show plenty of affection, thriving on spending as much time with you as possible. They’re also known for their high energy levels, intelligence, and protective instincts — these loyal dogs will also tend to choose one person in their family to form a deep bond with. 

As such, it’s best to equally distribute feeding and grooming regimens with everyone, so your pooch won’t become too familiar with just one member of the family. Apart from this, the Boxmas can be great family pets that can open their hearts to strangers. Finally, their short coats will need regular brushing to help them keep clean and fresh.  

Mastiff Husky Mix

These designer dogs are a mix between the Mastiff and the Siberian Husky, which can bond well with their families, owners, and even children. As long as they’re socialized at a young age, they should be able to get along with other animals. This dog is a highly intuitive breed and will need firm and clear leadership to help them thrive in your home. 

They’re also quite independent, so they could become stubborn if their owner is too soft and loose with house rules. While these dogs are quite healthy, they will still come with a few health problems such as Entropion, Cardiomyopathy, and Hip Dysplasia. Apart from these worries, they are loyal, loving, and smart companions who can be great family dogs. 


If you’re after a large dog that wants nothing more than cuddles, then consider the Mastidoodle — these gentle giants are here to protect your family while staying by your side. These protective dogs will voluntarily guard you and your family while being wonderful watchdogs. They are wonderful cuddle-buddies who are highly affectionate to both kids and adults, but will still need supervision because of their big frames. 

The Mastidoodle is an active dog and will need regular exercise, so be sure to spend a lot of time going out with them and expend their energy. This is a quick-witted breed and will need a variety of training drills and repetitive exercises to keep them from getting bored. They can also get attached to their owners and will need training and socialization to help them become adjusted to living at home.    

Mountain Mastiff

The Mountain Mastiff is a mix between the Bernese Mountain Dog and the Mastiff, which has an appearance that makes it easily mistaken for a fluffy Mastiff or a Saint Bernard. As such, these dogs can bring a unique combination that you can add to the family. They are known as sensitive, kind, and loving dogs — their even temperament makes them among the few gentle giants that exist in the dog world. 

As such, they’re a great choice for families with other pets and older children. These canines are naturally wary of strangers while at the same time, they’re highly eager to please their owners. Despite their calm nature, they still need socialization and training just like any other dog because their size might be a bit too much for some people. Positive reinforcement is a good idea for training these dogs. 


If you’re after a friendly couch potato, then you’ve found a friend in the Daniff, a cross between the Mastiff and the Great Dane which would like nothing more than to spend time with their loved ones. They also love the outdoors, so they’re best suited for people who can meet their exercise needs. They’re great with kids but you will still need to supervise them just as you would any other dog, especially since they’re so big. 

While Daniffs aren’t as vigilant as other Mastiff mixes, they are capable of warning their owners when they feel danger around a situation or a stranger. These dogs are very smart too, so you may struggle with their stubbornness during training, but you can be sure that they’re worth it. Luckily, these pups will get the work done as long as you offer them a yummy treat! 

FAQs About Mastiff Mixed Breeds

Below are a few of the most common questions about this giant breed, and all the other mixes that it can create. 

Are they Easy to Train? 

Because Mastiffs are so eager to please, they will thoroughly enjoy training and they’re also known for being soft and gentle, so you won’t see them become aggressive. That said, they’re still dogs and should never be subjected to scolding or other negative training strategies. The best way to handle them is through rewards-based training, giving them plenty of praise and treats from time to time. 

Do they Bark a Lot?

If you don’t like excessive barking, then the Mastiff is a great match for you. These well-mannered and calm dogs are loved for their mild temperament, which makes them a great fit for families. But even if they’re quiet they can still be terrific watchdogs; they just won’t bark as much compared to others. 


All in all, Mastiff mixed breeds are very protective, loving, and mostly relaxed dogs that want nothing more than to spend their days with their owners and families. No matter which pup you choose, know that you’ll be taking home a good-natured and well-mannered dog that will be a wonderful addition to your home. However, before you make a commitment to caring for one of these dogs, remember that these massive dogs will need plenty of space to move around in and will need lots of exercise to keep them in good health.